You can remove a breakpoint that you have previously added to a tuple while leaving the rest of the sequence intact.
Open Breakpoints Window
Main Menu: Window ▶ Debugging ▶ Breakpoints Keyboard: Alt+Shift+5
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Remove the Breakpoint
Right click on the breakpoint you want to remove from the tuple and select Complex Breakpoint ▶ Remove from MyTuple… from the pop-up menu, where MyTuple is the name of the sequence containing the breakpoint you are removing.